Equipment - liquid handling

Gilson Flexus is a state-of-the-art robotic platform

Sophisticated and flexible liquid handling capabilities with robotic manipulation. The open architecture of Flexus allows for simple plug’n’play integration of a variety of peripheral devices that enable complete protocols to be automated. Separate robotic and pipetting arms ensures that robotic function can work independently to increase throughput and efficiency. The Flexus system in the Immunoassay Biomarker Core Laboratory has 2 robotic arms; the first is a 270° rotating microplate gripper, to turn a plate for cross pipetting or improved access to other modules on or off the deck and can increase deck capacity by stacking plates; and the second is a pipetting arm with 8 individual washable tip probes (volume range 1μl - 1ml), it has individual Y and Z movement with individual level sensors.

CyBi-Well Pipettor Device

A fixed head, disposable tip pipettor for 96 well formats for volume ranges from 0.2µL to 1000µL. The pipettor is ideal for high throughput screening (HTS) or research environments. It is ideal for reformatting, replication and plate coating.

The system in the Immunoassay Biomarker Core Laboratory has a 5-position moving plate track carriage with space for processed plates and other accessories such as tip washing stations or reagent reservoirs and two chimney plate stackers.

4 x 96 plates to 1 x 384 plate













Fluid X XSP-200 Single Channel Sample Processor

The XSP-200 liquid handling and sample formatting workstation provides flexible system that can be used without the need for programming. You only need to provide a simple work list on Excel (converted to CSV format). You are able to cherry pick your samples individually for liquid handling or as a full 96 format. The Immunoassay Biomarker Core Laboratory has the workstation primarily set up to pipette from Eppendorf tube [the platform has special Eppendorf sample tube holders will hold the bent open caps back out of the way] into 96 microplates or 1.2ml tubes (96 format).  The volume range for pipetting is 10µl to 1.0ml. Our instrument is fitted with disposable tip option. Each tip once used is expended into biological waste bag therefore no contamination of samples.

Multidrop Combi Reagent Dispenser

Thermo Scientific™ Multidrop™ Combi Reagent Dispenser, designed to support the varied requirements of pharmaceutical and biotechnology laboratories. It combines the most versatile features for reagent dispensing with excellent performance for drug discovery or genomic and proteomic assays. It handles a wide selection of plates and volume range and provides fast dispensing and high-throughput operation. The instrument is intended for automated dispensing of up to eight different reagents simultaneously. Provides precise dispensing over a 0.5 to 2500μL range, ensuring reproducible assay data. It can accommodate microplates from 6 to 1536 wells and plate heights of 5 to 50mm.  Minimal dead volume and back-flushing reduces reagent costs. It uses eight-channel detachable and autoclavable dispensing cassettes that are standard across the multidrop range.

Various Adjustable Tip Spacing Multichannel

The Thermo Scientific E1- ClipTip Electronic Adjustable Tip Spacing Multichannel Equalizer pipettes perform sample transfers between virtually any tube, rack, microplate or horizontal gel box quickly and efficiently. Adjustable tip spacing allows you to set the distance between tips by simply sliding the scale to expand or contract to the desired labware format. Volume range available within the Immunoassay Biomarker Core Laboratory is 2µl to 1250µl covered by two electronic adjustable multichannel pipettes.


4titude 4s3 variabe Temperature Thermal Sealer 

The 4s3 is a semi-automatic thermal sealer which is compatible with a wide range of seals and plates or 96 individually racked tubes of differing designs and heights.  With variable temperature and time settings, sealing conditions are easily optimised to produce a 100% seal, eliminating sample loss. Plate and seal are placed on the holder, the "Operate" button pressed and the drawer automatically closes.  The sealing process is controlled by an electric mechanism. This unique feature eliminates operator variation, giving a consistent seal every time and reducing the damage caused to microplates by over-sealing.

96 INDI™ Seal enables sealing of certain Polypropylene 96well format round well plates or 96 individually racked tubes, such as cluster racks and 2D barcoded racked tubes.