The Tayside Bioresource is a portfolio of individual studies that have been recruiting participants from Tayside to genetic research since 1997. As of January 2012, 40,000 individuals (10% of total Tayside population), have been recruited to these research studies and their DNA has been donated for future research, with the aim of improving the prevention, diagnosis and treatment of a wide range of serious and life-threatening illnesses – including cancer, heart diseases, stroke, diabetes, arthritis, osteoporosis, eye disorders, depression and forms of dementia. Each of these studies involved a great deal of effort and expense to put together, but have shown the utility of having a bioresource linked to the rich clinical datasets which are unique to Tayside.
With the recent funding from the Wellcome Trust we are now exploring the use of “spare blood” in research, and we are seeking population-wide pre-consent for the storage and analysis of blood samples that are taken in routine clinical care. Over a three year period over three quarters of the population of Tayside will have a blood sample taken for one reason or another. This project is known as GoSHARE.
Researchers from around the UK and internationally are studying these DNA samples to determine the role of genes in both disease susceptibility and the effectiveness of treatments.