Professor Marion E T McMurdo

Professor (Clinical)

Address:

Medical Research Institute/Cardiovascular and Diabetes

Ageing and Health
Mail Box 1
Level 7
Ninewells Hospital
Dundee

Phone Number:

+(44) 01382 383086

Email Address:

m.e.t.mcmurdo@dundee.ac.uk

Biography

Professor and Head of Ageing and Health at the University of Dundee and a consultant geriatrician. She leads a multidisciplinary team of researchers examining the role of exercise, physical activity and nutrition in sarcopenia and age-related functional decline. She is renowned for a highly successful track record in completing large clinical trials in frail older populations. She was appointed as UK Chair of the National Institute for Health Research Ageing Research group in 2009 and has published over 150 peer reviewed papers.

With Miss Dorothy Dobson, she co-founded of D D Developments Ltd, a University of Dundee not-for-profit organisation which provides evidence-based exercise classes for older people throughout the UK.

She has won a number of accolades, including the Lady Illingworth Prize in 2001 (an award made to the UK clinician considered to have made the greatest contribution to improving the quality of life of older people through research) and in 2005 she was identified by the British Medical Association as one of 14 leading UK academic role models. A firm believer in good communication, she delivers regular free lectures to packed halls of older people around the UK. In 2011 she won the Ian Stevenson award for excellence in public engagement with science.

Research

Leader of a research team focused on postponing/preventing disability in later life. Expert in competing high quality clinical trials in frail older people, and in recruiting to time and target. Interventions include: nutrition (including vitamins D and K), drug treatments for sarcopenia, exercise/physical activity training.

Other research:  sedentary behaviour, influences on physical activity participation, recruitment of 'hard to study' populations.

UK Chair of NIHR Age and Ageing Speciality research group 2009-present

Publications

  • Burton L, Sumukadas D, Witham M, Struthers AD, McMurdo MET. Effect Of Spironolactone On Physical Performance In Older People With Self-Reported Physical Disability. Am J Med 2013;126 (7): 590-597. IF 5.430, rank 13/155 (General and Internal Medicine)
  • Beveridge L, Struthers AD McMurdo MET, Witham MD. Allopurinol use is associated with greater functional gains in older rehabilitation patients. Age Ageing (in press)
  • Sniehotta FF, Gellert P, Witham MD, Donnan PT, Crombie IK, McMurdo MET. Psychological theory in an interdisciplinary context: How do social cognitions predict physical activity in older adults alongside demographic, health-related, social, and environmental factors? Int J Behaviour Nutr Physical Activity (in press).
  • Tan SC, Ramage L, McMurdo MET, Witham MD. Predicting failure to improve during rehabilitation for older patients using routinely collected clinical data. Eur Geriatr Med 2013;http://dx.doi.org/10.1016/j.eurger.2013.06.009.
  • Witham MD, Price RG, Struthers AD, Donnan PT, Messow C, Ford I, McMurdo MET. Cholecalciferol to reduce blood pressure in older patients with isolated systolic hypertension. JAMA Intern Med 2013 online August 12
  • Sumukadas D, Millar S, Band M, Cvoro V, MacConnachie A, Witham MD, Struthers AD, McMurdo MET. Do ACE inhibitors improve the response to exercise training in functionally impaired older adults?: a randomised controlled trial. J Gerontol A Biol Med Sci doi:10.1093/gerona/glt142 IF 4.314, rank 6/46.
  • Witham, Sayer A, Siddal H, McMurdo MET. ACE inhibitors, statins and thiazides: no association with change in grip strength among community dwelling older men and women in Hertfordshire Cohort Study. Age Ageing 2013 (in press).
  • Sumukadas D, Mangoni A, McMurdo MET, Guthrie B. Temporal trends in anticholinergic medication prescription in older people: repeated cross-sectional analysis of population prescribing data. Age Ageing 2013 (in press).
  • Hughes L, McMurdo MET, Guthrie B. Guidelines for people not for diseases: the challenges of applying UK clinical guidelines to people with multimorbidity. Age Ageing 2013;42:62-69.
  • McMurdo MET. Participation and the older population. Public Service Review: Health and Social Care: issue 35, 74, 2013.
  • McMurdo MET. Clinical research must include more older people. BMJ 2013;346:f3899
  • McMurdo MET, Witham MD. Unnecessary ward moves. Age Ageing 2013; 42:555-556.
  • Cooney GM, Dwan K, Greig CA, Lawlor DA, Rimer J, Waugh FR, McMurdo MET, Mead GE. Exercise for depression. Cochrane Database of Systematic Reviews 2013, Issue 9. Art. No.: CD004366. DOI: 10.1002/14651858.CD004366.pub6.
  • Carroll SL, Greig CA, Lewis SJ, McMurdo MET, Sniehotta FF, Johnston M, Johnston DW, Mead GE. The use of pedometers in stroke survivors: are they feasible and how well to they detect steps? Arch Phy Med Rehabil 2012:93(3):466-70.
  • Witham MD, Dryburgh M, Sugden J, Sumukadas D, McMurdo MET. A comparison of the Endurance Shuttle Walk Test and the Six Minute Walk test for assessment of exercise capacity in older people. Ageing Clin Exp Res 2012;24:176-180.
  • Witham MD, Roberta L Fulton, C Greig, Johnston DW, Lang CC, Van der Pol M, Boyers D, Struthers AD, McMurdo MET. Efficacy and cost-effectiveness of an exercise programme for functionally impaired older heart failure patients – a randomized controlled trial. Circ Heart Failure 2012;5:209-216. IF 4.315, rank 22/114 (Cardiac and cardiovascular)
  • McMurdo MET, Argo I, Crombie IK, Feng Z, Sniehotta FF, Vadiveloo T, Witham MD, Donnan PT. Social, environmental and psychological factors associated with objective physical activity levels in the over 65s. PLoS ONE 2012;7(2):e31878. Doi:10.1371/journal.pone.0031878. IF 4.411.
  • Sumukadas D, Habicht D, McMurdo MET.  Proton Pump Inhibitors are associated with lower magnesium levels in older people with chronic kidney disease. J Am Geriatr Soc 2012 Feb;60(2):392-3
  • Burton L, Witham MD, Struthers AD, McMurdo MET, Sumukadas D. Influence of Iron status on physical function in older people.  J Aging Res Clin Practice 2012
  • Lynch J, Henderson N, Witham MD, Ramage R, McMurdo MET. Association between statin medication use and improved outcomes during inpatient rehabilitation in older people Age and Ageing 2012;41:260-262. 
  • Carroll SL, Greig CA, Lewis SJ, McMurdo MET, Sniehotta FF, Johnston M, Johnston DW, Mead GE. The use of pedometers in stroke survivors: are they feasible and how well to they detect steps? Arch Phy Med Rehabil 2012:93(3):466-70. 
  • Witham MD, Dryburgh M, Sugden J, Sumukadas D, McMurdo MET. A comparison of the Endurance Shuttle Walk Test and the Six Minute Walk test for assessment of exercise capacity in older people. Ageing Clin Exp Res 2012;24:176-180. 
  • Witham MD, Roberta L Fulton, C Greig, Johnston DW, Lang CC, Van der Pol M, Boyers D, Struthers AD, McMurdo MET. Efficacy and cost-effectiveness of an exercise programme for functionally impaired older heart failure patients – a randomized controlled trial. Circ Heart Failure 2012;5:209-216. IF 4.315, rank 22/114 (Cardiac and cardiovascular) 
  • McMurdo MET, Argo I, Crombie IK, Feng Z, Sniehotta FF, Vadiveloo T, Witham MD, Donnan PT. Social, environmental and psychological factors associated with objective physical activity levels in the over 65s. PLoS ONE 2012;7(2):e31878. Doi:10.1371/journal.pone.0031878. IF 4.411. 
  • Molloy GJ, O'Carroll RE, Witham MD, McMurdo MET. Interventions to enhance adherence to medications in patients with heart failure: a systematic review. Circ Heart Fail 2012; 5:126-33. 
  • Nicholson S, Sniehotta FF, van Wijck F, Grieg CA, Johnston M, McMurdo MET, Dennis M. A systematic review of perceived barriers and motivators to physical activity after stroke. Int J Stroke 2012;1747-4949.2012.00880. 
  • Guthrie B, Payne K, Alderson P, McMurdo MET, Mercer S. Adapting clinical guidelines to take account of multimorbidity. BMJ 2012;345;22-24. 
  • Mead GE, Morley W, Campbell P, Greig CA, McMurdo MET, Lawlor DA. Exercise for depression. Cochrane Database Syst Rev. 2012 Jul 8;(3):CD004366. Review. IF 6.186, rank 10/153.
  • Sumukadas D, Habicht D, McMurdo MET.  Proton Pump Inhibitors are associated with lower magnesium levels in older people with chronic kidney disease. J Am Geriatr Soc 2012 Feb;60(2):392-3
  • McMurdo MET, Roberts H, Parker S, Wyatt N, May H, Goodman C, Jackson S, Gladman J, O’Mahony S, Ali K, Dickinson E, Edison P, Dyer C on behalf of the Age and Ageing Specialty Group, NIHR, Comprehensive Clinical Research Network. Improving recruitment of older people to research through good practice. Age Ageing 2011;40:659-665.
  • Burton L, McMurdo MET, Struthers AD. Mineralocorticoid antagonism: a novel way to treat sarcopenia and physical impairment in older people. Clin Endocrinology 2011; 75(6): 725-729 IF 3.323, rank 44/116 (Endocrinology and metabolism).
  • Witham MD, Ramage L, Hanslip J, Gillespie ND, Burns S, McMurdo MET.  Trends in function and post-discharge mortality in a Medicine for the Elderly rehabilitation centre over a 10 year period. Arch Phys Med Rehabil 2011;92:1288-92.
  • McMurdo MET, Sugden J, Argo I, Boyle P, Johnston DW, Sniehotta FF, Donnan PT. Do pedometers increase physical activity in sedentary older women? A randomised controlled trial. JAGS 2010;58:2099-2106.  IF 3.656, rank 1/25
  • Witham MD, Crighton L, Gillespie ND, Struthers AD, McMurdo MET. The effects of Vitamin D supplementation on physical function and quality of life in older heart failure patients: a randomised controlled trial. Circulation Heart Failure 2010;3:195-201. IF 4.315, rank 22/114 (Cardiac and cardiovascular)
  • Barnett,K.N, Ogston,S.A, McMurdo MET, Morris AD, Evans JM. A 12-year follow-up study of all-cause and cardiovascular mortality among 10,532 people newly diagnosed with Type 2 diabetes in Tayside. Diabet Med 2010; 27(10): 1124-29. IF 2.871, rank 46/105 (Endocrinology and metabolism).
  • McMurdo MET, Price RJG, Potter J, Shields M, Stott D. Should oral nutritional supplementation be given to undernourished older people on hospital discharge? A controlled trial. JAGS 2009;57:2239-2245.  IF 3.085, rank 9/36 (Geriatric and Gerontology).
  • Mead GE, Morley W, Campbell P, Greig CA, McMurdo MET, Lawlor DA. Exercise for depression. Cochrane Database Syst Rev. 2009 Jul 8;(3):CD004366.
  • Sumukadas D, Witham MD, Struthers AD, McMurdo MET. Day length and weather conditions profoundly affect physical activity levels in older functionally impaired people. J Epidemiol Community Health 2009;63:305-309. IF 3.186 rank 18/105 (Public, environmental and occupational health).
  • Molloy GJ, Gao C, Johnston DW, Johnston M, Struthers AD, McMurdo MET. Adherence to ACE inhibitors and illness beliefs in older heart failure patients. Eur J Heart Failure 2009; 11(7): 715-20. IF 3.398, rank 21/78 (Cardiology and cardiovascular).
  • McMurdo MET, Argo I, Phillips G, Daly F, Davey PG. Cranberry or trimethoprim for the prevention of recurrent urinary tract infections? A randomised controlled trial in older women. J Antimicrob Chemother 2008;63:389-395.
  • Evans JMM, Barnett KN, McMurdo MET, Morris AD. Reporting of diabetes on death certificates on 1,872 people with type 2 diabetes in Tayside, Scotland. European J Public Health 2008 Apr;18(2):201-3. IF 1.481, ranking 59/98 (Public health).
  • Sugden JA, Sniehotta F, Donnan PT, Boyle P, Johnston DW, McMurdo MET. The feasibility of using pedometers and brief advice to increase activity in sedentary older women – a pilot study. BMC Health Services Research 2008, 8:169. IF 1.36. 
  • Abellan Van Kan G, Sinclair A, Older Rikkert M, Gambassi G, Vella B, McMurdo MET and Gerontonet Collaboration. The geriatric minimum data set for clinical trials (GMDS). J Nutr Health Aging 2008;12:197-200. 
  • Molloy GJ, Johnston DW, Johnston M, Gao C, Witham MD, Struthers AD, McMurdo MET. Using the demand-led model of job strain to predict caregiver burden in the informal caregivers of heart failure patients. Br J Health Psychol 2008 Sep;13(Pt 3):401-17. IF 1.586. 
  • Witham MD, Daykin A, McMurdo MET. Pilot study of an exercise intervention suitable for older heart failure patients with left ventricular systolic dysfunction – a pilot study. Eur J Cardiovasc Nursing 2008;
  • Witham MD, Fulton R, Wilson L, Leslie CA, McMurdo MET. Validation of an individualised quality of life measure in older day hospital patients. Health Qual Life Outcomes 2008 Dec;7(4): 303-6.
  • Sumukadas D, Witham MD, Struthers AD, McMurdo MET. Effect of perindopril in elderly people with functional impairment: a randomised controlled trial. CMAJ 2007;177 (8): 867-74. IF 7.4. *Winner of the Bruce P Squires award for 2007 from the Canadian Medical Association Journal.
  • Bolton-Smith C, McMurdo MET, Paterson CR, Mole PA, Harvey J, Fenton ST, Prynne CJ, Shearer MJ. A two-year randomized controlled trial of phylloquinone (vitamin K1) and vitamin D3 plus calcium on the bone health of older women. J Bone Mineral Res 2007;22:509-519.
  • Witham MD, Argo IS, Johnston DW, Struthers AD, McMurdo MET. Long term follow-up of very old heart failure patients enrolled in a trial of exercise training. Am J Geriatr Cardiol 2007;16:243-248. IF, rank (Cardiology and cardiovascular). 
  • Barnett KN, Ogston SA, McMurdo MET, Morris AD, Evans JMM. An 11 year follow-up study of mortality and cause of death in 11,125 people with newly diagnosed type 2 diabetes. Diabetic Medicine 2007;24:12-14.
  • Crombie IK, Irvine L, Williams B, Slane PW, McGinnis AR, Slane PW, Alder EM, McMurdo MET.  Why older people do not participate in leisure time physical activity: a survey of activity levels, beliefs and deterrents. Age Ageing 2004;33: 287-292.
  • Hutcheon SD, Gillespie ND, Crombie IK, Struthers AD, McMurdo MET. Perindopril improves 6-minute walking distance in very old patients with left ventricular systolic dysfunction: a randomised double blind placebo controlled trial. Heart 2002;88:373-377.
  • Mather AS, Rodriguez C, McHarg AM, Reid IC, McMurdo MET. A randomised controlled trial of the effects of exercise on depressive symptoms in older people with poorly responsive depressive disorder. British Journal of Psychiatry 2002;180:411-415.

Teaching

Responsible for teaching of the Medicine of Old Age to undergraduates.

Block organiser for Year 4 Ageing and Health attachment (40 weeks per year) and Year 5 Foundation programme Preparation Course (1 week per year).

External tutor since 1989 to WHO/UN International Institute on Ageing for healthcare professionals from developing countries.

PhD Supervision

1992 PhD Gillian Cunningham, pharmacist, Robert Gordon University

1997 MSc Elaine Gray, nurse, Dundee University

2001 PhD Petra Kliempt, nurse, Dundee University

2002 MSc Anne Mather, nurse, Dundee University

2003 MD Stuart Hutcheon, doctor, Dundee University

2003 MSc Rosemary Price, dietician, University of Dundee

2005 PhD Miles Witham, doctor, Dundee University

2006 MD Deepa Sumukadas, doctor, Dundee University

2009 PhD Karen Barnett, psychologist, Dundee University

2010 MD Louise Burton, doctor, Dundee University

2011 MSc Roberta Fulton, nurse, Dundee University (ongoing)

2012 PhD Michael Thomson, nurse, Dundee University (ongoing)

Conferences

External tutor to WHO/United Nations International Institute on Ageing in Malta 1989 to present

  1. Maintaining physical function: exercise and new roles for old drugs - November 2009. 

    Keynote lecture 7th Malta Medical Conference, Malta

     
  2. Sarcopenia – what is it and does it matter – April 2011

    Royal College of Physicians of Edinburgh

     
  3. Research supervision – October 2011

    British Geriatrics Society, Brighton

     
  4. Opportunity of a generation: the NIHR Age and ageing specialty group - November 2011.

    South Yorkshire CLRN Showcasing Ageing, Sheffield.

     
  1. Physical activity in later life. Keynote address NICE Knowledge Exchange Conference – May 2012.

    Toronto University, Canada

     
  2. Interactions between individual, social, behavioural and environmental influences on physical activity – August 2012.

    World Congress on Active Ageing, Glasgow SECC.

     
  3. Off legs is not a diagnosis – 29 January 2013

    Royal College of Physicians of Edinburgh

     
  4. What’s new in drug treatment for sarcopenia? – 9 July 2013

    Congress Centre, London. Sarcopenia 2013 conference.

     
  5. NHS clinicians and research: the final frontier – 20 November 2013.

    British Geriatrics Society, Harrogate.

     
  6. Delivering research for ageing population – 9 December 2013.

    Royal College of Physicians of London.