Mr. Kevin Roth

Postgraduate Student

Address:

Jacqui Wood Cancer Centre
James Arrott Drive
Ninewells Hospital & Medical School
Dundee
DD1 9SY

Email Address:

k.roth@dundee.ac.uk

Biography

2007 – 2010 BSc student, Molecular Biotechnology, Heidelberg University

2010 – 2011 Research technician, BASF Plant Science

2011 – 2015 MSc student, Molecular Biosciences, Heidelberg University

2015 MSc thesis, German Cancer Research Center (DKFZ), Heidelberg

Since Oct 2015 PhD student, University of Dundee, School of Medicine, Division of Cancer Research

Research

Research

My research is focussing on Epigenetics in non-melanoma skin cancer and how mutations of Tet (Ten-eleven-translocases) enzymes are influencing DNA methylation.

We therefore will use UV induced skin tumors of mice to map DNA methylation on a global scale. We further will use cell culture models to test the effect of Tet knock-down and over-expression on global DNA methylation levels.

Publications

Carlina acaulis has antioxidant effects and ameliorates beta-amyloid toxicity in a C. elegans model

Pille Link · Kevin Roth · Michael Wink

Alzheimer's Association International Conference (AAIC), Copenhagen; 07/2014

 

 

Impact of Soy Isoflavones on the Epigenome in Cancer Prevention

Maria Pudenz · Kevin Roth · Clarissa Gerhauser

Nutrients 10/2014; 6(10):4218-4272. DOI:10.3390/nu610421