Cancer is characterised by genetic mutations that lead to uncontrolled cell proliferation, resistance to cell death and cell migration. The molecular and cellular processes that underlie these changes are the focus of our research.
We study the responses of cells to stresses such as environmental toxins, DNA damage and the disruption of cell division, which can promote the genetic alterations that lead to cancer.
We also study the responses of cancer cells to chemotherapeutic drugs and radiation.
We have particular expertise in the molecular and cellular biology of cell signalling, DNA damage, drug metabolism, cell proliferation and cell death.