Grade of Post/Salary: £33,131 - £49,091
Duration of employment: This is a full time position with the expectation of a 3 year term. The post is offered for one year in the first instance, it is expected that the fellow will apply for external clinical fellowship funding within the first year.
The University of Dundee enjoys an international reputation for excellence that attracts top-class students and academics from across the world – with over 140 countries represented in the University community.
The focus of this Wellcome Trust funded clinical fellowship will be on the physiological mechanisms of metformin action. The fellow will learn skills in phenotyping including undertaking and analysis of tracer studies to evaluate glucose absorption, hepatic and whole body insulin sensitivity, PET imaging, and analysis of the microbiome and metabolome in relation to metformin action. The research undertaken will be discussed and shaped with the successful applicant, but may include initial pilot studies in year 1 to establish feasibility before undertaking two intervention studies. One will recruit people who carry are variant in SLC2A2 (GLUT2) that we have shown alters glycaemic response to metformin, the other will study patients with recently diagnosed diabetes and investigate the physiological, metabolomics and microbiome changes with metformin initiation. Whilst funding is available for 3 years, it is anticipated the fellow will apply for an external clinical training fellowship during the first year of this post. It is anticipated the clinical fellow will register for a PhD at the start of this post.
Essential Knowledge and Experience
- MB BS or equivalent primary medical qualification
- GMC registration and entry on the appropriate GMC Specialist Register
- Completed medical training to ST2/3
- Experience of clinical research
- Experience of writing scientific reports with published papers and/or scientific abstracts
- An interest in understanding variability in phenotype and drug response in patients with diabetes
Potential applicants are encouraged to have an informal discussion about the post with Professor Ewan Pearson email@example.com
Please see full job description for further information.